Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide
Nature Communications
September 2023
Gut Microbiota–Derived Trimethylamine N-Oxide Contributes to Abdominal Aortic Aneurysm Through Inflammatory and Apoptotic Mechanisms
Circulation
April 2023
Trimethylamine N-oxide is associated with long-term mortality risk: the multi-ethnic study of atherosclerosis
European Heart Journal
March 2023
Relationship between Plasma Trimethylamine N-Oxide Levels and Renal Dysfunction in Patients with Hypertension
Karger
July 2021
Gut Microbiota-Derived Trimethylamine N-Oxide and Kidney Function: A Systematic Review and Meta-Analysis
American Society for Nutrition
May 2021
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms
eLife
October 2020
Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulo…
Basic Sciences
May 2020
Development Of A Gut Microbe–Targeted Nonlethal Therapeutic To Inhibit Thrombosis Potential
Nature Medicine
September 2018
Advanced Chronic Kidney Disease Populations Have Elevated Trimethylamine N-Oxide Levels Associated With Increased Cardiovascular Events
www.kidney-international.org
May 2016
Serum Trimethylamine-N-Oxide is Elevated in CKD and Correlates with Coronary Atherosclerosis Burden
J Am Soc Nephrol
May 2016
Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease
PLOS ONE
January 2016
Gut Microbiota-Dependent Trimethylamine N-Oxide (TMAO) Pathway Contributes to Both Development of Renal Insufficiency and Mortality Risk in Chronic Kidney Disease
Circulation Research
September 2014
Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk
Massachusetts Medical Society
April 2013